Two sample MR report
ETS2_Conventional Dendritic Cell against UKB-b-18436
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 3 | -0.1288360 | 0.4563569 | 0.8248319 |
| Weighted median | 3 | 0.0527827 | 0.0219911 | 0.0163867 |
| Inverse variance weighted | 3 | 0.0512133 | 0.0177289 | 0.0038685 |
| Simple mode | 3 | 0.0560568 | 0.0245174 | 0.1495383 |
| Weighted mode | 3 | 0.0559547 | 0.0264344 | 0.1685041 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 0.0179196 | 1 | 0.8935101 |
| Inverse variance weighted | 0.1738137 | 2 | 0.9167625 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| 0.077627 | 0.1966064 | 0.7606021 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 5.43e-05 | 0 | TRUE | 0.4855985 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
